ea0090p71 | Diabetes, Obesity, Metabolism and Nutrition | ECE2023
Sarray Sameh
, Dallel Meriem
, Ben lamine Laila
, Sellami Nejla
, Turki Amira
, Brock Roland
, Ghorbel mohamed
Aims: Genetic variations mediating matrix metalloproteinase-2 (MMP-2) expression may result in individual differences in susceptibility to particular diseases. Our aim was to investigate the possible association of certain MMP-2 gene variants with type 2 diabetes mellitus (T2DM) in a Tunisian population.Subjects and Methods: A case-control study involving 310 normoglycemic control subjects and 791 T2D patients was performed. A total of four MMP-2 SNPs (-...